27-3-2024

TP53 variant classification

Thomas van Overeem Hansen is a molecular biologist and professor in functional genomics at the Clinical Genetics Department at Rigshospitalet, Copenhagen, Denmark. He is a member of the InSiGHT - ClinGen Hereditary CRC/Polyposis Variant Curation Expert Panel and a member of the national germline cancer variant classification group in Denmark.

The webinar will provide an overview of ClinGen TP53 Expert Panel Specifications to the ACMG/AMP Variant Interpretation Guidelines including the use of in silico, clinical and functional data for TP53 variant classification. In addition, the webinar will provide information regarding the Danish experience with national classification of TP53 variants.

Registration: https://attendee.gotowebinar.com/register/1490147654034718044