PTEN - Mar 2019

Project title:
Toward a more accurate cancer risk assessment in germline PTEN mutation carriers

Project leader(s):
Dr. Janet Vos and Prof. Nicoline Hoogerbrugge, Radboudumc

Project Description:
The aim of this project study was to provide accurate cancer risk estimates for PHTS patients to assess genotype based cancer risks to pave the way for more personalised care regarding risk management and treatment.

This project is part of the INSPECT study: Investigation into PTEN-related cancer and phenotype. The INSPECT study is a retrospective cohort study with prospective follow-up via cancer registries and questionnaires. This cohort study will include PHTS families known at the expertise centres participating in ERN GENTURIS as well as families known at collaborative centres of the national ERN GENTURIS centres.

In total 14 ERN GENTURIS Full Members and Affiliated Partners, and 2 Supporting Partners from the UK contributed.

Start date: March 2019

Duration: 2.5 years

Funder: PTEN Research Foundation

Link study page: https://pten.eu